Aspirus Cardiologist on How GLP-1 Medications May Reduce Heart Attack and Stroke Risk
Growing evidence shows benefits beyond diabetes and weight loss
2/9/2026
Dr. Daniel Krause, Aspirus Cardiologist
Heart disease is the leading cause of death in the United States, yet many heart attacks and strokes can be prevented. During Heart Month, Dr. Daniel Krause, a cardiologist with Aspirus Heart Care, is helping explain how GLP-1 receptor agonist medications may play a role in reducing heart disease risk for some patients.
GLP-1 medications were originally developed to treat type 2 diabetes and are now widely known for helping with weight loss. Over the past several years, large clinical studies have shown that these medications can also reduce the risk of serious heart-related events, including heart attack and stroke, particularly in people with diabetes or other cardiovascular risk factors.
“From a cardiology standpoint, GLP-1 medications have become another important tool we can use to help lower future heart risk in the right patients,” Krause said.
Research shows GLP-1 medications help improve blood sugar levels and may also have positive effects on weight, blood pressure, and cholesterol. Together, these changes can reduce strain on the heart and lower the risk of long-term cardiovascular problems.
“When someone has diabetes, pre-diabetes, obesity, or other risk factors, we can calculate their overall heart risk and decide whether this type of medication makes sense as part of a prevention plan,” Krause said.
Krause emphasized that GLP-1 medications are not appropriate for everyone and should be considered alongside lifestyle changes such as healthy eating, physical activity, and routine medical care.
He also stressed the importance of paying attention to symptoms and seeking care early.
“One of the biggest challenges we see is people waiting too long to get checked out,” Krause said. “Chest pain with activity, shortness of breath, or swelling in the legs are signs you should talk with a provider sooner rather than later.”
During Heart Month, Aspirus Health encourages individuals to talk with their primary care provider or cardiologist about heart disease risk factors and available prevention options, including whether GLP-1 medications may be appropriate as part of their care plan.
Learn more about heart and vascular care at https://www.aspirus.org/heart-vascular-services.
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