Aspirus Regional Cancer Center

Cancer Clinical Trials

This is a current listing of active clinical trials at the Aspirus Regional Cancer Center. From this list you can select a specific cancer that you are interested in (for example, breast or colon cancer) and then review the clinical trials that are active at the Aspirus Regional Cancer Center for that specific disease.

Breast Cancer

Trial Name: A Phase III Clinical Trial Comparing the Combination of Docetaxel Plus Cyclophosphamide to Anthracycline-Based Chemotherapy Regimens for Women with Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer.

Protocol ID: NSABP B49

Eligibility:

Eligible

  • Patients must be female.
  • Must be > 18 yrs. old.
  • The tumor must be unilateral invasive adenocarcinoma of the breast on histologic examination.
  • The breast cancer must be HER2 negative.
  • Patients must have undergone either a total mastectomy or breast-conserving surgery (lumpectomy).
  • Patients must meet required laboratory values.

 

Ineligible

  • Evidence of metastatic disease.
  • Any history of ipsilateral invasive breast cancer or ipsilateral DCIS.
  • History of non-breast malignancies within 5 years prior to entry into the study, except for the following: carcinoma in situ of the cervix, colorectal carcinoma in situ, melanoma in situ, and basal cell and squamous cell carcinomas of the skin.
  • Previous therapy with anthracyclines or taxanes for any malignancy.
  • Chemotherapy administered for the currently diagnosed breast cancer prior to study entry.
  • History of hypersensitivity reaction to drugs formulated with polysorbate 80.

Unstable diabetes mellitus.

Enrollment: 1843 women

Benefits:

Taking part in this study may or may not make your health better.  While doctors hope that the combination of docetaxel and cyclophosphamide is as good as the other combinations of standard chemotherapy for treating breast cancer, there is no proof of this yet.  The information from this study could help future breast cancer patients.

Contact:

These clinical trial overviews are intended to provide a brief overview of the clinical trial. To help determine whether the trial is appropriate for you, the major eligibility criteria are listed above. To obtain more information on the eligibility and the treatment plan, please contact our Oncology Clinical Research Coordinator, Beth Knetter at 715-847-2353 or 1-800-283-2881, ext.72353.

Created: Jan 18, 2013

Updated: Jan 18, 2013

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